Home

Recent Publication

2023

Cryo-EM structures of ATP-bound hydrolysis-deficient EQ2 mutants of E. coli EttA,

Cryo-EM studies of the four E. coli paralogs establish ABCF proteins as master plumbers of the peptidyl-transferase center of the ribosome

Shikha Singh, Riley C. Gentry, Ziao Fu, Nevette A. Bailey, Clara G. Altomare, Kam-Ho Wong, Matthew J. Neky, Chi Wang, Korak Kumar Ray, Ying-Chih Chi, Zhening Zhang, Robert A. Grassucci, Joachim Frank, Grègory Boël, Ruben L Gonzalez Jr., John F. Hunt III

2022

Structures and population distributions in global conformational ensemble reconstructions (GCERs) of G551D-6SS-hCFTR.

Mechanism of dual pharmacological correction and potentiation of human CFTR

Chi Wang, Zhengrong Yang, Blaine J. Loughlin, Haijin Xu, Guido Veit, Sergey Vorobiev, Oliver B. Clarke, Fan Jiang, Yaohui Li, Shikha Singh, Zachary Rich, Elizabeth R. Menten, Robert A. Grassucci, Wei Wang, Allison Mezzell, Ziao Fu, Kam-Ho Wong, Jing Wang,
Diana R. Wetmore, R. Bryan Sutton, Christie G. Brouillette, Ina L. Urbatsch, John C. Kappes, Gergely L. Lukacs, Joachim Frank, John F. Hunt
Oligomeric interactions maintain active-site structure in a noncooperative enzyme family

Oligomeric interactions maintain active-site structure in a noncooperative enzyme family

Yaohui Li, Rongzhen Zhang, Chi Wang, Farhad Forouhar, Oliver B Clarke, Sergey Vorobiev, Shikha Singh, Gaetano T Montelione, Thomas Szyperski, Yan Xu, John F Hunt
PubMed
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex

Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex

Malkeet Singh Bahia, Netaly Khazanov, Qingxian Zhou, Zhengrong Yang, Chi Wang, Jeong S Hong 5, Andras Rab, Eric J Sorscher, Christie G Brouillette, John F Hunt, Hanoch Senderowitz
PubMed

2021

ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis

ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis

Jitender Mehla , George Liechti , Randy M Morgenstein , J Harry Caufield , Ali Hosseinnia , Alla Gagarinova , Sadhna Phanse , Norman Goodacre , Mary Brockett , Neha Sakhawalkar , Mohan Babu , Rong Xiao , Gaetano T Montelione , Sergey Vorobiev , Tanneke de
PubMed
Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator

Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator

Malkeet Singh Bahia, Netaly Khazanov, Qingxian Zhou, Zhengrong Yang, Chi Wang, Jeong S Hong, Andras Rab, Eric J Sorscher, Christie G Brouillette, John F Hunt, Hanoch Senderowitz
PubMed

2020

ABC-F translation factors: from antibiotic resistance to immune response

ABC-F translation factors: from antibiotic resistance to immune response

Corentin R Fostier , Laura Monlezun , Farès Ousalem , Shikha Singh , John F Hunt , Grégory Boël
PubMed

2019

CFTR: New insights into structure and function and implications for modulation by small molecules

CFTR: New insights into structure and function and implications for modulation by small molecules

Bertrand Kleizen a, John F. Hunt b, Isabelle Callebaut c, Tzyh-Chang Hwang d, Isabelle Sermet-Gaudelus e, Sylvia Hafkemeyer f, David N. Sheppard g
PubMed
High-Throughput PIXE as an Essential Quantitative Assay for Accurate Metalloprotein Structural Analysis: Development and Application

High-Throughput PIXE as an Essential Quantitative Assay for Accurate Metalloprotein Structural Analysis: Development and Application

Geoffrey W Grime , Oliver B Zeldin , Mary E Snell , Edward D Lowe , John F Hunt , Gaetano T Montelione , Liang Tong , Edward H Snell , Elspeth F Garman
PubMed
Featured Publication

No results

There are no publications with the provided filters.

    Sort Publications By